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NEXUS TRE™

AORTIC ARCH STENT GRAFT SYSTEM
Custom-Made Device

Engineered For The Most Demanding Aortic Region

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Product Highlights

  • 100% percutaneous treatment possible for a minimally invasive approach

  • Elimination of the need for supra-aortic debranching

  • Three vessels feeding the brain to replicate the anatomy of the native aorta
  • 20F low profile delivery system

Product Overview

Design Features Delivery System
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1. OPTIMIZED BLOOD FLOW WITH INTEGRATED BRANCH DESIGN

Optimize flow by maximizing the main lumen, ensuring smooth antegrade blood flow, reducing turbulence, and promoting efficient hemodynamics to lower cardiac workload.1

2. DOCK & LOCK TECHNOLOGY™

Two distal struts with locking latches open inside the dock, providing mechanical fixation to create a 25 mm sealing length with a 20% oversize.

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3. STENTS INWARDLY BENT TO MINIMIZE WALL STRESS

Tips of the stents oriented along the outer curve of the ascending aorta are bent inwards to provide a traumatic interface between the stent graft and the aortic wall.

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4. INNER BRANCH DESIGN FOR CAROTID AND SUBCLAVIAN

The inner branch delivers sealing and fixation zones for the covered stent. Its retrograde design allows for transfemoral introduction of all components while supporting future reinterventions from the supra-aortic vessels.

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THE NEXUS® PLATFORM IS A BIMODULAR SYSTEM DESIGNED TO MIMIC THE ASCENDING AND ARCH ANATOMY
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1. PRE-SHAPED CATHETER TO MINIMIZE ARCH MANIPULATION

Designed to follow the natural curves of the aortic arch to reduce manipulation and improve stent conformability during deployment.

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2. AIR EMBOLISM REDUCTION THROUGH ADVANCED DUAL FLUSHING PORTS

The dual flushing ports in the delivery system are designed to maximize air removal from the sheath, a risk factor for stroke.2

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3. LOW PROFILE 20 F SYSTEM ENGINEERED TO REDUCE ACCESS COMPLICATION

NEXUS® is the lowest profile Arch Stent, delivered completely transfemoral reducing the risk of stroke compared to neck access.3

4. PRE-WIRED INNER BRANCHES FOR EASY ACCESS

Preloaded Guide Wires ensures access to the inner branch of the stent graft to reduce manipulation and time of intervention.

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References

  1. Sengupta S, Hamady M, Xu XY. Haemodynamic Analysis of Branched Endografts for Complex Aortic Arch Repair. Bioengineering (Basel). 2022 Jan 18;9(2):45. doi: 10.3390/bioengineering9020045. PMID: 35200399; PMCID: PMC8868591.
  2. Data on file
  3. Association of upper extremity and neck access with stroke in endovascular aortic repair Plotkin, Anastasia et al. Journal of Vascular Surgery, Volume 72, Issue 5, 1602 – 1609

NEXUS TRE™ Aortic Arch Stent Graft is a custom-made device based on the existing NEXUS® Aortic Arch Stent Graft System, a CE marked endovascular branch system for the aortic arch NEXUS® is a registered trademark of Endospan Ltd.

All products and indications are not available/approved in all markets. All trademarks are owned by Artivion, Inc. or its subsidiaries. On-X Life Technologies, Inc., Jotec GmbH, and Ascyrus Medical GmbH are wholly owned subsidiaries of Artivion, Inc. MWENG0052.000. (2025-01)

Endospan Ltd, 4 Maskit St., Herzliya 4673304, Israel